Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.52 |
| ▸ | DRD3 | P35462 | 4/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558181 | 0.88 | S1PR1 (0.50) | DRD2DRD3S1PR1ALDH1A1GAA | |
| SCHEMBL8416073 | 0.86 | DRD2 (0.55) | DRD2DRD3S1PR1ALDH1A1GAA | |
| SCHEMBL8414050 | 0.83 | DRD2 (0.54) | DRD2DRD3S1PR1HDAC1NPC1 | |
| Hydrochloric Acid SCHEMBL8576067 | 0.83 | HDAC1 (0.54) | DRD2DRD3S1PR1ALDH1A1HDAC1 | |
| SCHEMBL8561767 | 0.82 | S1PR1 (0.45) | DRD2DRD3S1PR1HDAC1MEN1 | |
| SCHEMBL12209953 | 0.82 | S1PR1 (0.62) | DRD2DRD3S1PR1HDAC1NPC1 | |
| SCHEMBL177341 | 0.81 | S1PR1 (0.76) | DRD2DRD3S1PR1HDAC1 | |
| SCHEMBL1410264 | 0.79 | DRD2 (0.45) | DRD2DRD3S1PR1ALDH1A1HDAC1 | |
| SCHEMBL8415376 | 0.79 | DRD2 (0.58) | DRD2DRD3S1PR1HDAC1NPC1 | |
| SCHEMBL8564103 | 0.79 | S1PR1 (0.42) | DRD2DRD3S1PR1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880284-A | HAVING ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASES-INHIBITING EFFECTS | DR. KARL THOMAE GMBH (DE) | 1999-03-09 | — | — | US | disclosed |
| US-5681841-A | PREVENTION CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1997-10-28 | — | — | US | disclosed |