Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT2 | P31751 | 5/20 | 0.41 |
| ▸ | AKT1 | P31749 | 4/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | QPCT | Q16769 | 6/20 | 0.34 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417112 | 0.96 | AKT1 (0.38) | AKT2AKT1HRH3EPHX2QPCT | |
| SCHEMBL8416026 | 0.88 | ITGB3 (0.35) | AKT2AKT1HRH3QPCTQPCTL | |
| SCHEMBL8574007 | 0.85 | ITGB3 (0.39) | HRH3EPHX2QPCTQPCTL | |
| SCHEMBL8414282 | 0.84 | ITGB3 (0.37) | QPCTQPCTL | |
| SCHEMBL8576047 | 0.82 | HRH3 (0.38) | HRH3EPHX2QPCTQPCTL | |
| SCHEMBL8575601 | 0.82 | HRH3 (0.36) | HRH3EPHX2QPCTQPCTL | |
| SCHEMBL8572857 | 0.81 | HRH3 (0.37) | HRH3EPHX2QPCTQPCTL | |
| Hydrochloric Acid SCHEMBL8577042 | 0.81 | HRH3 (0.35) | HRH3EPHX2QPCTQPCTLADRB2 | |
| SCHEMBL8577438 | 0.81 | HRH3 (0.35) | AKT1HRH3EPHX2QPCTQPCTL | |
| SCHEMBL8577440 | 0.80 | HRH3 (0.35) | HRH3EPHX2QPCTQPCTL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880284-A | HAVING ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASES-INHIBITING EFFECTS | DR. KARL THOMAE GMBH (DE) | 1999-03-09 | — | — | US | disclosed |
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |
| US-5681841-A | PREVENTION CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1997-10-28 | — | — | US | disclosed |