Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | CYP26B1 | Q9NR63 | 4/20 | 0.35 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | QPCT | Q16769 | 6/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8416026 | 0.96 | ITGB3 (0.35) | ITGB3ITGA2BPPARDPPARACYP26B1 | |
| SCHEMBL8417112 | 0.88 | AKT1 (0.38) | QPCTQPCTLCA1CA2 | |
| SCHEMBL8571601 | 0.85 | ITGB3 (0.40) | ITGB3ITGA2BPPARDPPARAQPCT | |
| SCHEMBL8417044 | 0.84 | AKT2 (0.41) | QPCTQPCTL | |
| SCHEMBL8575186 | 0.81 | ITGB3 (0.37) | ITGB3ITGA2BPPARDPPARAQPCT | |
| SCHEMBL8571822 | 0.81 | PPARD (0.38) | ITGB3ITGA2BPPARDPPARAQPCT | |
| SCHEMBL8576418 | 0.81 | FFAR1 (0.38) | ITGB3ITGA2BPPARDPPARACYP26B1 | |
| SCHEMBL8573927 | 0.79 | RXRA (0.36) | ITGB3ITGA2BPPARDPPARAQPCT | |
| SCHEMBL8577135 | 0.77 | S1PR1 (0.43) | PPARDPPARAQPCTFFAR1FFAR4 | |
| SCHEMBL8572786 | 0.77 | QPCT (0.38) | ITGB3ITGA2BQPCTQPCTL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880284-A | HAVING ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASES-INHIBITING EFFECTS | DR. KARL THOMAE GMBH (DE) | 1999-03-09 | — | — | US | disclosed |
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |
| US-5681841-A | PREVENTION CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1997-10-28 | — | — | US | disclosed |