Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | QPCT | Q16769 | 5/20 | 0.31 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.31 |
| ▸ | PPIA | P62937 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417112 | 0.82 | AKT1 (0.38) | HRH3AKT1EPHX2QPCTQPCTL | |
| SCHEMBL8417044 | 0.81 | AKT2 (0.41) | HRH3AKT1EPHX2QPCTQPCTL | |
| SCHEMBL7284335 | 0.80 | HRH3 (0.39) | HRH3AKT1EPHX2PPIADRD2 | |
| SCHEMBL8575601 | 0.79 | HRH3 (0.36) | HRH3EPHX2QPCTQPCTL | |
| SCHEMBL8574007 | 0.79 | ITGB3 (0.39) | HRH3EPHX2QPCTQPCTL | |
| SCHEMBL8576047 | 0.78 | HRH3 (0.38) | HRH3EPHX2QPCTQPCTL | |
| SCHEMBL8577440 | 0.78 | HRH3 (0.35) | HRH3EPHX2QPCTQPCTL | |
| SCHEMBL8572857 | 0.77 | HRH3 (0.37) | HRH3EPHX2QPCTQPCTL | |
| SCHEMBL8571038 | 0.75 | QPCT (0.38) | HRH3EPHX2QPCTQPCTL | |
| Hydrochloric Acid SCHEMBL8577042 | 0.75 | HRH3 (0.35) | HRH3EPHX2QPCTQPCTL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |