Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8419430 | 0.95 | TSHR (0.37) | TSHRPOLBALOX15 | |
| SCHEMBL8421434 | 0.92 | RXFP1 (0.36) | RXFP1ALOX15 | |
| SCHEMBL8419128 | 0.92 | TSHR (0.38) | TSHRPOLBALOX15 | |
| SCHEMBL8422201 | 0.90 | ALOX15 (0.40) | POLBALOX15 | |
| SCHEMBL8417387 | 0.88 | PLA2G2A (0.37) | TSHRRXFP1POLB | |
| SCHEMBL8417991 | 0.88 | ALOX15 (0.34) | ALOX15 | |
| SCHEMBL8421430 | 0.86 | RIPK1 (0.37) | RIPK1TLR8TLR7 | |
| SCHEMBL8417426 | 0.85 | TSHR (0.37) | TSHRPOLBALOX15 | |
| SCHEMBL8417950 | 0.84 | ALOX15 (0.35) | ALOX15 | |
| SCHEMBL8417917 | 0.84 | TSHR (0.39) | TSHRPOLBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962491-A | ANGIOTENSIN ANTAGONIST, HYPOTENSIVE AGENTS, CARDIOVASCULAR DISORDERS, STROKES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5703110-A | HYPOTENSIVE AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-12-30 | — | — | US | disclosed |