Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 1/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 2/20 | 0.32 |
| ▸ | USP14 | P54578 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 2/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8419593 | 0.91 | FDFT1 (0.49) | FDFT1CYP4Z1 | |
| SCHEMBL8420062 | 0.89 | FDFT1 (0.47) | FDFT1 | |
| SCHEMBL8420013 | 0.89 | FDFT1 (0.48) | FDFT1HRH3CYP4F2CYP4A11CYP4Z1 | |
| SCHEMBL8419682 | 0.87 | FDFT1 (0.46) | FDFT1SYK | |
| SCHEMBL8417676 | 0.86 | FDFT1 (0.44) | FDFT1HRH3 | |
| SCHEMBL8419759 | 0.86 | FDFT1 (0.44) | FDFT1 | |
| SCHEMBL8421697 | 0.85 | FDFT1 (0.43) | FDFT1PDE3BPDE3AP2RY12 | |
| SCHEMBL8421885 | 0.85 | FDFT1 (0.43) | FDFT1HRH3CASRADRB2CYP2D6 | |
| SCHEMBL8420486 | 0.84 | FDFT1 (0.43) | FDFT1 | |
| SCHEMBL8968794 | 0.84 | FDFT1 (0.67) | FDFT1HRH3CYP4F2CYP4A11CYP4Z1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919793-A | QUINUCLIDINE DERIVATIVES, SQUALENE SYNTHETASE INHIBITORS, ANTICHOLESTEROL AGENTS | ZENECA LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |