Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8419593 | 0.86 | FDFT1 (0.49) | FDFT1GAAHSD17B10ALDH1A1POLB | |
| SCHEMBL8420031 | 0.85 | FDFT1 (0.42) | FDFT1SMN1; SMN2ALDH1A1HPGDLMNA | |
| SCHEMBL8919905 | 0.84 | FDFT1 (0.41) | FDFT1GAASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL8420062 | 0.84 | FDFT1 (0.47) | FDFT1 | |
| SCHEMBL8419682 | 0.84 | FDFT1 (0.46) | FDFT1PTPN1KDM4EALDH1A1HPGD | |
| SCHEMBL8419833 | 0.83 | PTPN1 (0.38) | FDFT1PTPN1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL8418559 | 0.81 | ATM (0.44) | FDFT1KDM4EGAAHSD17B10SMN1; SMN2 | |
| SCHEMBL8419759 | 0.81 | FDFT1 (0.44) | FDFT1SMN1; SMN2ALDH1A1MEN1MAPK1 | |
| SCHEMBL8419863 | 0.80 | FDFT1 (0.34) | FDFT1KDM4E | |
| SCHEMBL8419678 | 0.80 | FDFT1 (0.39) | FDFT1SMN1; SMN2ALDH1A1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919793-A | QUINUCLIDINE DERIVATIVES, SQUALENE SYNTHETASE INHIBITORS, ANTICHOLESTEROL AGENTS | ZENECA LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |