Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8419128 | 0.89 | TSHR (0.38) | ALOX15 | |
| SCHEMBL8502175 | 0.89 | ALOX15 (0.34) | ALOX15 | |
| SCHEMBL8505253 | 0.87 | MAPT (0.32) | ALOX15 | |
| SCHEMBL8417950 | 0.86 | ALOX15 (0.35) | ALOX15 | |
| SCHEMBL8422201 | 0.85 | ALOX15 (0.40) | ALOX15 | |
| SCHEMBL8419430 | 0.83 | TSHR (0.37) | ALOX15 | |
| SCHEMBL8417428 | 0.82 | RIPK1 (0.37) | ALOX15 | |
| SCHEMBL8417855 | 0.80 | ALOX15 (0.36) | ALOX15 | |
| SCHEMBL8419277 | 0.80 | ALOX15 (0.36) | ALOX15 | |
| SCHEMBL8417991 | 0.80 | ALOX15 (0.34) | ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962491-A | ANGIOTENSIN ANTAGONIST, HYPOTENSIVE AGENTS, CARDIOVASCULAR DISORDERS, STROKES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5763619-A | HYPOTENSIVE AGENTS, CARDIOVASCULAR DISORDERS OR STROKES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| US-5705517-A | ANGIOTENSIN II ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-01-06 | — | — | US | disclosed |
| US-5703110-A | HYPOTENSIVE AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-12-30 | — | — | US | disclosed |