Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | FAP | Q12884 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9765534 | 0.82 | PREP (0.53) | FAPDPP4DPP8DPP7 | |
| SCHEMBL7610256 | 0.82 | ALDH1A1 (0.42) | FAPALDH1A1KMT2AMEN1DPP4 | |
| Hydrochloric Acid SCHEMBL3847558 | 0.81 | ALDH1A1 (0.42) | FAPALDH1A1KMT2AMEN1DPP4 | |
| SCHEMBL4889705 | 0.75 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1TP53MAPK1 | |
| SCHEMBL11157104 | 0.74 | ACE (0.51) | FAPALDH1A1KMT2AMAPK1 | |
| SCHEMBL10589596 | 0.74 | PREP (0.52) | KMT2AMEN1DPP4DPP8DPP7 | |
| SCHEMBL5575952 | 0.74 | PREP (0.52) | KMT2AMEN1DPP4DPP8DPP7 | |
| SCHEMBL8419532 | 0.71 | PLK1 (0.53) | PLK1ALDH1A1KMT2A | |
| Glycyl Proline SCHEMBL10589539 | 0.70 | CYP1A2 (0.43) | ALDH1A1KMT2AMEN1DPP4DPP8 | |
| SCHEMBL18681280 | 0.70 | DPP4 (0.47) | FAPDPP4DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791071-B1 | ASSAY FOR PROLINE IMINOPEPTIDASE AND OTHER HYDROLYTIC ACTIVITIES | LITMUS CONCEPTS INC (US) | 1999-09-15 | — | — | EP | disclosed |
| EP-0791071-A1 | ASSAY FOR PROLINE IMINOPEPTIDASE AND OTHER HYDROLYTIC ACTIVITIES | LITMUS CONCEPTS, INC. (US) | 1997-08-27 | — | — | EP | disclosed |
| US-5571684-A | SOLID PHASE CONJUGATE | LITMUS CONCEPTS, INC. (US) | 1996-11-05 | — | — | US | disclosed |
| WO-1996015255-A2 | ASSAY FOR PROLINE IMINOPEPTIDASE AND OTHER HYDROLYTIC ACTIVITIES | LITMUS CONCEPTS, INC. (US) | 1996-05-23 | — | — | WO | disclosed |