SCHEMBL9765534

SCHEMBL9765534

NCC(=O)N1CCC[C@H]1C(=O)NC(=O)c1cccc2ccccc12

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PREP P48147 5/20 0.53
FAP Q12884 2/20 0.53
DPP8 Q6V1X1 2/20 0.53
DPP9 Q86TI2 1/20 0.53
LMNA P02545 1/20 0.45
POLB P06746 1/20 0.45
NTMT1 Q9BV86 1/20 0.45
BCHE P06276 1/20 0.44
DRD4 P21917 3/20 0.43
DPP4 P27487 3/20 0.43
DPP7 Q9UHL4 3/20 0.43
SCN5A Q14524 1/20 0.43
SCN2A Q99250 1/20 0.43
KCNH2 Q12809 1/20 0.42
GAA P10253 1/20 0.41
KDM2B Q8NHM5 1/20 0.41
GPR6 P46095 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8417702 0.82 PLK1 (0.46) FAPDPP8DPP4DPP7
SCHEMBL11114114 0.82 NTMT1 (0.58) NTMT1GAA
SCHEMBL5575952 0.80 PREP (0.52) PREPDPP8POLBBCHEDRD4
SCHEMBL10589596 0.80 PREP (0.52) PREPDPP8POLBBCHEDRD4
SCHEMBL10844332 0.80 PREP (0.55) PREPFAPDPP8DPP9DRD4
SCHEMBL7610256 0.78 ALDH1A1 (0.42) FAPDPP8DPP4DPP7KDM2B
Hydrochloric Acid SCHEMBL3847558 0.77 ALDH1A1 (0.42) FAPDPP8DPP4DPP7KDM2B
SCHEMBL22811230 0.74 FAP (0.67) PREPFAPDPP8DPP9DPP7
SCHEMBL380892 0.73 HTT (0.52) DPP8POLBDPP4DPP7
SCHEMBL10589601 0.73 HTT (0.52) DPP8POLBDPP4DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0122023-A1 Microorganisms detection methods and the separation of agglutinated microorganisms, and a kit for use therein E-Y LABORATORIES, INC. (US) 1984-10-17 EP claimed
US-RE33635-E Enzymatic assay method TOYO JOZO KABUSHIKI KAISHA (JP) 1991-07-09 US disclosed
EP-0330374-A2 Method for the colorimetric determination of DPP-IV using cinnamaldehyde PROTOTEK, INC., (US) 1989-08-30 EP disclosed
US-4681841-A CONSUMING OXYGEN OR GENERATING A PIGMENT; MEASUREMENT BY AN OXYGEN ELECTRODE OR COLORIMETRIC ASSAY TOYO JOZO KABUSHIKI KAISHA (JP) 1987-07-21 US disclosed
EP-0122028-A1 Colorimetric assay for enzymes, diagnostic article therefor and a method for forming such article E-Y LABORATORIES, INC. (US) 1984-10-17 EP disclosed
EP-0122023-A1 Microorganisms detection methods and the separation of agglutinated microorganisms, and a kit for use therein E-Y LABORATORIES, INC. (US) 1984-10-17 EP disclosed