Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.40 |
| ▸ | PPARD | Q03181 | 3/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | LSS | P48449 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10903534 | 0.87 | ALDH1A1 (0.46) | PPARAPPARDADORA3ALDH1A1TSHR | |
| SCHEMBL1434444 | 0.76 | KMT2A (0.45) | PPARAPPARDPPARGFFAR1FFAR4 | |
| SCHEMBL8605223 | 0.76 | ITGB3 (0.47) | PPARAPPARDALDH1A1CYP1A2 | |
| SCHEMBL23754112 | 0.71 | PPARG (0.45) | PPARAPPARDADORA3PPARGNPSR1 | |
| SCHEMBL11540230 | 0.71 | ALDH1A1 (0.44) | PPARAADORA3ALDH1A1PPARGLMNA | |
| SCHEMBL27571634 | 0.70 | GAA (0.44) | PPARAPPARDADORA3PPARGMEN1 | |
| SCHEMBL6754623 | 0.70 | PPARA (0.40) | PPARAPPARDADORA3ALDH1A1PPARG | |
| SCHEMBL10903315 | 0.70 | ALDH1A1 (0.34) | ALDH1A1TSHRHTT | |
| SCHEMBL11763480 | 0.70 | PPARG (0.44) | PPARAPPARDADORA3PPARGNPSR1 | |
| SCHEMBL2554944 | 0.69 | MAPT (0.50) | PPARAADORA3ALDH1A1PPARGHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919793-A | QUINUCLIDINE DERIVATIVES, SQUALENE SYNTHETASE INHIBITORS, ANTICHOLESTEROL AGENTS | ZENECA LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025459-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |