Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4842048 | 0.84 | CA5A (0.58) | CYP4F2CYP4A11PDK2ALDH1A1GAA | |
| SCHEMBL5738807 | 0.84 | CA5A (0.51) | CYP4F2CYP4A11PDK2ALDH1A1GAA | |
| SCHEMBL13111290 | 0.82 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL2126108 | 0.81 | CYP4F2 (0.43) | CYP4F2CYP4A11PDK2ALDH1A1GAA | |
| SCHEMBL30154424 | 0.81 | CYP4F2 (0.43) | CYP4F2CYP4A11PDK2ALDH1A1GAA | |
| SCHEMBL2127345 | 0.81 | CYP4F2 (0.43) | CYP4F2CYP4A11PDK2ALDH1A1GAA | |
| SCHEMBL31260444 | 0.80 | ALDH1A1 (0.51) | CYP4F2CYP4A11ALDH1A1GAAGFER | |
| SCHEMBL2124578 | 0.80 | RXRA (0.43) | CYP4F2CYP4A11PDK2ALDH1A1GAA | |
| SCHEMBL2125942 | 0.80 | LMNA (0.43) | CYP4F2CYP4A11PDK2ALDH1A1GAA | |
| SCHEMBL7420742 | 0.80 | GAA (0.55) | CYP4F2CYP4A11PDK2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138901-A1 | CARBOXYLIC ACID-CONTAINING COMPOUNDS, DERIVATIVES THEREOF, AND RELATED METHODS OF USE | BIOGEN IDEC MA INC (US) | 2010-12-02 | — | — | WO | disclosed |
| WO-2010138901-A1 | CARBOXYLIC ACID-CONTAINING COMPOUNDS, DERIVATIVES THEREOF, AND RELATED METHODS OF USE | BIOGEN IDEC MA INC (US) | 2010-12-02 | — | — | WO | disclosed |