SCHEMBL8417824

SCHEMBL8417824

Cn1c(OCC2CCCO2)n[nH]c1=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
BRD4 O60885 1/20 0.43
HPGD P15428 2/20 0.39
ALOX15 P16050 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CYP2C9 P11712 2/20 0.39
CYP2C19 P33261 2/20 0.39
CYP1A2 P05177 1/20 0.39
NPC1 O15118 4/20 0.39
RAB9A P51151 4/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
KDM4E B2RXH2 2/20 0.38
GRIN1 Q05586 1/20 0.38
GRIN2B Q13224 1/20 0.38
CYP3A4 P08684 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
GPR84 Q9NQS5 2/20 0.37
LMNA P02545 1/20 0.37
POLB P06746 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16324213 0.78 MAOA (0.43) BRD4
SCHEMBL13015458 0.70 BRD4 (0.48) ALDH1A1BRD4HPGDALOX15HSD17B10
SCHEMBL13954882 0.70 BRD4 (0.48) ALDH1A1BRD4HPGDALOX15HSD17B10
SCHEMBL16519569 0.69 MAOB (0.52) ALDH1A1HPGDHSD17B10NPC1RAB9A
SCHEMBL3211179 0.69 NOTUM (0.35) ALDH1A1HPGDHSD17B10SMN1; SMN2KDM4E
SCHEMBL7552091 0.68 ADORA2A (0.32) NPC1RAB9A
SCHEMBL13355036 0.68 GPR84 (0.46) ALDH1A1BRD4HPGDNPC1RAB9A
SCHEMBL13354918 0.66 ALDH1A1 (0.48) ALDH1A1BRD4ALOX15HSD17B10CYP2C9
SCHEMBL13354926 0.66 ALDH1A1 (0.48) ALDH1A1BRD4ALOX15HSD17B10CYP2C9
SCHEMBL8113479 0.65 ADORA1 (0.44) BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6001776-A FOR THE SELECTIVE COMBATING OF MONOCOTYLEDON AND DICOTYLEDON WEEDS IN MONOCOTYLEDON AND DICOTYLEDON CROPS, BOTH PRE-EMERGENCE AND POST-EMERGENCE BAYER AKTIENGESELLSCHAFT (DE) 1999-12-14 US disclosed
EP-0842171-A1 HERBICIDAL SULPHONYLAMINO(THIO)CARBONYL TRIAZOLIN(THI)ONES WITH HETEROCYCLYL(ALK)OXY SUBSTITUENTS BAYER AG (DE) 1998-05-20 EP disclosed
WO-1997003981-A1 HERBICIDAL SULPHONYLAMINO(THIO)CARBONYL TRIAZOLIN(THI)ONES WITH HETEROCYCLYL(ALK)OXY SUBSTITUENTS BAYER AKTIENGESELLSCHAFT (DE) 1997-02-06 WO disclosed