Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | EEF2K | O00418 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8418045 | 0.94 | LMNA (0.43) | LMNANPSR1EEF2KALDH1A1ATM | |
| SCHEMBL8421496 | 0.94 | LMNA (0.42) | LMNANPSR1EEF2KALDH1A1ATM | |
| SCHEMBL8418155 | 0.92 | TBXAS1 (0.43) | NPSR1EEF2KALDH1A1ATML3MBTL1 | |
| SCHEMBL8421709 | 0.91 | LMNA (0.43) | LMNANPSR1EEF2KALDH1A1ATM | |
| SCHEMBL8419600 | 0.90 | EEF2K (0.36) | NPSR1EEF2KALDH1A1ATML3MBTL1 | |
| SCHEMBL8417294 | 0.89 | LMNA (0.45) | LMNANPSR1EEF2KALDH1A1ATM | |
| SCHEMBL8418158 | 0.87 | LMNA (0.43) | LMNANPSR1EEF2KALDH1A1ATM | |
| SCHEMBL8418033 | 0.87 | LMNA (0.45) | LMNANPSR1EEF2KALDH1A1ATM | |
| SCHEMBL8417508 | 0.86 | TBXAS1 (0.45) | NPSR1EEF2KALDH1A1ATML3MBTL1 | |
| SCHEMBL8419746 | 0.86 | LMNA (0.44) | LMNANPSR1EEF2KALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943606-A1 | BENZENESULFONAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME | HOKURIKU SEIYAKU CO., LTD. (JP) | 1999-09-22 | — | — | EP | disclosed |