Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 4/20 | 0.32 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.31 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.31 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417990 | 0.78 | LMNA (0.39) | LMNACYP2C19HIF1AKDM4EALDH1A1 | |
| SCHEMBL8564794 | 0.77 | LMNA (0.38) | LMNACYP2C19HIF1AKDM4EALDH1A1 | |
| SCHEMBL7594162 | 0.74 | LMNA (0.50) | LMNACYP2C19HIF1AKDM4EALDH1A1 | |
| SCHEMBL7590729 | 0.73 | LMNA (0.52) | LMNACYP2C19HIF1AKDM4EALDH1A1 | |
| SCHEMBL7592858 | 0.73 | LMNA (0.51) | LMNACYP2C19HIF1AMAP2K1MAP2K2 | |
| SCHEMBL6226822 | 0.72 | LMNA (0.46) | LMNACYP2C19HIF1AKDM4EALDH1A1 | |
| SCHEMBL7594751 | 0.72 | LMNA (0.46) | LMNACYP2C19HIF1AMAP2K1MAP2K2 | |
| SCHEMBL7587928 | 0.71 | LMNA (0.56) | LMNACYP2C19HIF1AMAP2K1MAP2K2 | |
| SCHEMBL7595621 | 0.70 | LMNA (0.44) | LMNACYP2C19HIF1AKDM4EALDH1A1 | |
| SCHEMBL7592788 | 0.70 | LMNA (0.44) | LMNACYP2C19HIF1AMAP2K1MAP2K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0782564-B1 | IODINATED X-RAY CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 1999-09-01 | — | — | EP | disclosed |