Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 4/20 | 0.31 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.31 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.31 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564791 | 0.80 | LMNA (0.39) | LMNACYP2C19HIF1AKDM4EALDH1A1 | |
| SCHEMBL8417993 | 0.77 | LMNA (0.38) | LMNACYP2C19HIF1AKDM4EALDH1A1 | |
| SCHEMBL7595391 | 0.74 | LMNA (0.51) | LMNACYP2C19HIF1AKDM4EALDH1A1 | |
| SCHEMBL7596337 | 0.71 | LMNA (0.48) | LMNACYP2C19HIF1AKDM4EALDH1A1 | |
| SCHEMBL7590944 | 0.70 | KDM4E (0.43) | LMNACYP2C19HIF1AKDM4EALDH1A1 | |
| SCHEMBL8562051 | 0.69 | LMNA (0.46) | LMNACYP2C19HIF1A | |
| SCHEMBL20329603 | 0.68 | ALDH1A1 (0.48) | LMNACYP2C19HIF1AKDM4EALDH1A1 | |
| SCHEMBL8562054 | 0.68 | LMNA (0.47) | LMNACYP2C19HIF1AMAP2K1 | |
| SCHEMBL7591779 | 0.67 | GAA (0.43) | LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL26054346 | 0.66 | ALDH1A1 (0.46) | LMNACYP2C19HIF1AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0782564-B1 | IODINATED X-RAY CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 1999-09-01 | — | — | EP | disclosed |