Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 16/20 | 0.53 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8805294 | 0.91 | KDM4E (0.49) | PLA2G2APPARGMEN1KMT2A | |
| SCHEMBL9054194 | 0.87 | PTGDR2 (0.56) | PLA2G2APLA2G1BMEN1KMT2A | |
| SCHEMBL8805164 | 0.81 | YES1 (0.52) | PLA2G2A | |
| SCHEMBL8804947 | 0.81 | KDM4E (0.54) | PLA2G2AMEN1KMT2A | |
| SCHEMBL8805925 | 0.78 | MAPT (0.54) | PLA2G2AMEN1KMT2A | |
| SCHEMBL9055101 | 0.76 | LMNA (0.69) | PLA2G2APLA2G1BMEN1KMT2A | |
| SCHEMBL8805948 | 0.76 | YES1 (0.66) | — | |
| SCHEMBL8805165 | 0.74 | KDM4E (0.45) | MEN1KMT2A | |
| SCHEMBL8805149 | 0.72 | YES1 (0.48) | — | |
| SCHEMBL8292857 | 0.71 | PLA2G2A (0.80) | PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965582-A | ANTIHISTAMINES | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1999-10-12 | — | — | US | claimed |
| WO-1996004266-A2 | INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1996-02-15 | — | — | WO | claimed |
| WO-1996004266-A2 | INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1996-02-15 | — | — | WO | disclosed |