Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.56 |
| ▸ | PLA2G2A | P14555 | 13/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8804947 | 0.94 | KDM4E (0.54) | PTGDR2PLA2G2AMEN1MAPTKMT2A | |
| SCHEMBL8805925 | 0.87 | MAPT (0.54) | PTGDR2PLA2G2AMEN1MAPTKMT2A | |
| SCHEMBL8418121 | 0.87 | PLA2G2A (0.53) | PLA2G2AMEN1KMT2APLA2G1B | |
| SCHEMBL9055101 | 0.85 | LMNA (0.69) | PLA2G2AMEN1MAPTKMT2APLA2G1B | |
| SCHEMBL8805294 | 0.85 | KDM4E (0.49) | PTGDR2PLA2G2AMEN1MAPTKMT2A | |
| SCHEMBL8296713 | 0.83 | PLA2G2A (0.77) | PTGDR2PLA2G2A | |
| SCHEMBL8805590 | 0.79 | YES1 (0.55) | PLA2G2AKMT2AKDM4ELMNA | |
| SCHEMBL2168842 | 0.74 | FAAH (0.64) | PTGDR2MEN1MAPTKMT2AKDM4E | |
| SCHEMBL8805746 | 0.73 | YES1 (0.69) | PLA2G2AMEN1KMT2ALMNA | |
| SCHEMBL10778316 | 0.73 | MAPT (0.59) | PTGDR2PLA2G2AMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004266-A2 | INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1996-02-15 | — | — | WO | disclosed |