Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27741015 | 0.79 | RIPK1 (0.60) | RIPK1CYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL28808824 | 0.77 | RIPK1 (0.65) | RIPK1CYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL27945599 | 0.76 | RIPK1 (0.46) | RIPK1CYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL27964869 | 0.76 | RIPK1 (0.46) | RIPK1CYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL8415836 | 0.73 | RIPK1 (0.36) | RIPK1CYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL27666213 | 0.70 | RIPK1 (0.46) | RIPK1CYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL27666222 | 0.70 | RIPK1 (0.46) | RIPK1CYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL27908471 | 0.69 | LMNA (0.32) | CYP3A4TSHR | |
| SCHEMBL8238473 | 0.67 | LMNA (0.34) | CYP3A4CYP2C9TSHR | |
| SCHEMBL26697028 | 0.67 | LMNA (0.49) | SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942541-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-08-24 | — | — | US | disclosed |
| US-5723646-A | Substituted amino acid amide derivatives their preparation and use as fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-03-03 | — | — | US | disclosed |