Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28808824 | 0.86 | RIPK1 (0.65) | RIPK1CYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL27945599 | 0.85 | RIPK1 (0.46) | RIPK1CYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL27666213 | 0.84 | RIPK1 (0.46) | RIPK1CYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL27666222 | 0.84 | RIPK1 (0.46) | RIPK1CYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL27964869 | 0.84 | RIPK1 (0.46) | RIPK1CYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL8418529 | 0.79 | RIPK1 (0.38) | RIPK1CYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL27665702 | 0.76 | RIPK1 (0.61) | RIPK1CYP1A2CYP2D6ALOX5TAAR1 | |
| SCHEMBL8415836 | 0.76 | RIPK1 (0.36) | RIPK1CYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL8238473 | 0.75 | LMNA (0.34) | — | |
| SCHEMBL26697028 | 0.74 | LMNA (0.49) | SMN1; SMN2KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101300239-A | 7- (2-amino-1-hydroxy-ethyl) -4-hydroxybenzothiazol-2 (3H) -one derivatives as beta 2 adrenoreceptor agonists | ASTRAZENECA AB (SE) | 2008-11-05 | — | — | CN | claimed |
| CN-101300239-A | 7- (2-amino-1-hydroxy-ethyl) -4-hydroxybenzothiazol-2 (3H) -one derivatives as beta 2 adrenoreceptor agonists | ASTRAZENECA AB (SE) | 2008-11-05 | — | — | CN | disclosed |