Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 2/20 | 0.77 |
| ▸ | CCR1 | P32246 | 13/20 | 0.65 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.58 |
| ▸ | CCR3 | P51677 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11601787 | 0.87 | KCNA3 (1.00) | KCNA3CCR1CCR3 | |
| SCHEMBL11611247 | 0.82 | KCNA3 (0.69) | KCNA3CCR1OPRM1CCR3 | |
| SCHEMBL9107132 | 0.80 | KCNA3 (0.86) | KCNA3CCR1CCR3 | |
| SCHEMBL2312804 | 0.79 | CCR1 (1.00) | KCNA3CCR1OPRM1CCR3 | |
| SCHEMBL8418585 | 0.79 | KCNA3 (0.62) | KCNA3CCR1OPRM1CCR3 | |
| Hydrochloric Acid SCHEMBL11629523 | 0.78 | CCR1 (0.98) | KCNA3CCR1OPRM1CCR3 | |
| SCHEMBL11732757 | 0.78 | KCNA3 (0.81) | KCNA3CCR1CCR3 | |
| SCHEMBL10697451 | 0.75 | SIGMAR1 (0.65) | KCNA3CCR1CCR3 | |
| SCHEMBL7744512 | 0.75 | OPRM1 (0.66) | KCNA3CCR1OPRM1 | |
| SCHEMBL6661392 | 0.74 | KCNA3 (0.77) | KCNA3CCR1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849762-A | Peripherally acting anti-pruritic opiates | ADOLOR CORPORATION (US) | 1998-12-15 | — | — | US | claimed |
| US-5888494-A | TOPICAL | ADOLOR CORPORATION (US) | 1999-03-30 | — | — | US | disclosed |
| US-5849762-A | Peripherally acting anti-pruritic opiates | ADOLOR CORPORATION (US) | 1998-12-15 | — | — | US | disclosed |