Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | GCK | P35557 | 6/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12349926 | 0.84 | CCR4 (0.49) | CCR4CYP2D6CYP1A2CYP2C9GRM1 | |
| SCHEMBL22838132 | 0.80 | CCR4 (0.49) | CCR4CYP2D6CYP1A2CYP2C9GRM1 | |
| SCHEMBL5462531 | 0.79 | CCR4 (0.60) | CCR4CYP2D6CYP1A2CYP2C9GRM1 | |
| SCHEMBL13351522 | 0.78 | FDPS (0.59) | FDPSGAAALDH1A1MAPTNPC1 | |
| SCHEMBL12894443 | 0.78 | CCR4 (0.44) | CCR4CYP2D6CYP1A2CYP2C9GRM1 | |
| SCHEMBL11994346 | 0.78 | CCR4 (0.50) | CCR4CYP2D6CYP1A2CYP2C9GRM1 | |
| SCHEMBL18884354 | 0.76 | CCR4 (0.49) | CCR4CYP2D6CYP1A2CYP2C9GRM1 | |
| SCHEMBL12869755 | 0.74 | CCR4 (0.47) | CCR4CYP2D6CYP1A2CYP2C9GRM1 | |
| SCHEMBL12190585 | 0.74 | L3MBTL1 (0.57) | CYP2D6CYP1A2CYP2C9GRM1CSNK2A2 | |
| SCHEMBL12894440 | 0.73 | CCR4 (0.46) | CCR4CYP2D6CYP1A2CYP2C9GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070142369-A1 | Combination of an H3 antagonist/inverse agonist and an appetite suppressant | SCHERING CORPORATION | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142369-A1 | Combination of an H3 antagonist/inverse agonist and an appetite suppressant | CNR2, GPR119, GLP1R | CCR4 1952/4885CYP2D6 1688/4885CYP1A2 1023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.