Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MC4R | P32245 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL8418146 | 0.96 | ADRA1D (0.39) | ADRA1DADRA1AADRA1BL3MBTL1LMNA | |
| SCHEMBL12312782 | 0.78 | CCR2 (0.42) | ADRA1DADRA1AADRA1BL3MBTL1MC4R | |
| SCHEMBL8402001 | 0.77 | ADRA1D (0.41) | ADRA1DADRA1AADRA1BL3MBTL1LMNA | |
| SCHEMBL8402249 | 0.77 | ADRA1D (0.41) | ADRA1DADRA1AADRA1BL3MBTL1LMNA | |
| SCHEMBL8402002 | 0.77 | ADRA1D (0.41) | ADRA1DADRA1AADRA1BL3MBTL1LMNA | |
| SCHEMBL17621809 | 0.76 | ITGB2 (0.33) | — | |
| SCHEMBL12337286 | 0.76 | CCR2 (0.41) | ADRA1DADRA1AADRA1BL3MBTL1LMNA | |
| SCHEMBL13907982 | 0.76 | ADRA1D (0.40) | ADRA1DADRA1AADRA1BL3MBTL1LMNA | |
| SCHEMBL28044432 | 0.76 | HRH3 (0.31) | — | |
| SCHEMBL7766973 | 0.75 | SMN1; SMN2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886181-A | ASYMMETRIC HYDROGENATION OF THE CORRESPONDING 1,4,5,6-TETRAHYDROPYRAZINES | LONZA, LTD. (CH) | 1999-03-23 | — | — | US | disclosed |