Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | FASN | P49327 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 5/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11711810 | 0.80 | EPHX2 (0.41) | SOAT2SOAT1FAAHEPHX2CES1 | |
| SCHEMBL8756382 | 0.80 | EPHX2 (0.41) | SOAT2SOAT1FAAHEPHX2CES1 | |
| SCHEMBL4934443 | 0.80 | EPHX2 (0.41) | SOAT2SOAT1FAAHEPHX2CES1 | |
| SCHEMBL8418702 | 0.79 | EPHX2 (0.44) | SOAT2SOAT1FAAHEPHX2CNR1 | |
| SCHEMBL8987951 | 0.78 | MEN1 (0.41) | SOAT2SOAT1FAAHEPHX2CES1 | |
| SCHEMBL11817004 | 0.74 | SOAT2 (0.45) | SOAT2SOAT1FASNFAAHEPHX2 | |
| SCHEMBL4609004 | 0.73 | SOAT2 (0.46) | SOAT2SOAT1FAAHEPHX2CES1 | |
| SCHEMBL4609010 | 0.73 | SOAT2 (0.46) | SOAT2SOAT1FAAHEPHX2CES1 | |
| Toluene SCHEMBL8986744 | 0.73 | SOAT2 (0.42) | SOAT2SOAT1FASNFAAHEPHX2 | |
| SCHEMBL489153 | 0.72 | MAOB (0.50) | SOAT2SOAT1FASNFAAHEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0360246-B1 | 3-Oxiranyl benzoic acids and derivatives thereof | SEARLE & CO (US) | 1994-03-30 | — | — | EP | claimed |
| US-5990326-A | AN ANTIINFLAMMATORY AGENT AS INHIBITORS OF LEUKOTRIENE HYDROLASE | G.D. SEARLE & CO. (US) | 1999-11-23 | — | — | US | disclosed |
| EP-0360246-B1 | 3-Oxiranyl benzoic acids and derivatives thereof | SEARLE & CO (US) | 1994-03-30 | — | — | EP | disclosed |
| EP-0360246-A1 | 3-Oxiranyl benzoic acids and derivatives thereof | G.D. Searle & Co. (US) | 1990-03-28 | — | — | EP | disclosed |