Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.44 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | PPARD | Q03181 | 4/20 | 0.43 |
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
| ▸ | F7 | P08709 | 4/20 | 0.43 |
| ▸ | F3 | P13726 | 4/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987951 | 0.85 | MEN1 (0.41) | EPHX2SOAT2SOAT1FAAHL3MBTL1 | |
| SCHEMBL4934443 | 0.83 | EPHX2 (0.41) | EPHX2SOAT2SOAT1FAAHCNR1 | |
| SCHEMBL8756382 | 0.83 | EPHX2 (0.41) | EPHX2SOAT2SOAT1FAAHCNR1 | |
| SCHEMBL11711810 | 0.83 | EPHX2 (0.41) | EPHX2SOAT2SOAT1FAAHCNR1 | |
| SCHEMBL9806367 | 0.80 | EPHX2 (0.41) | EPHX2SOAT2SOAT1FAAHCNR1 | |
| SCHEMBL8418706 | 0.79 | SOAT2 (0.42) | EPHX2SOAT2SOAT1FAAHCNR1 | |
| SCHEMBL4821584 | 0.79 | MEN1 (0.42) | EPHX2ALDH1A1L3MBTL1CYP3A4HPGD | |
| SCHEMBL20630456 | 0.78 | ALOX15 (0.49) | EPHX2SOAT2SOAT1FAAHCNR1 | |
| SCHEMBL20630498 | 0.76 | SOAT2 (0.49) | EPHX2SOAT2SOAT1FAAHCNR1 | |
| SCHEMBL808497 | 0.74 | MEN1 (0.41) | ALDH1A1L3MBTL1LMNACYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0360246-B1 | 3-Oxiranyl benzoic acids and derivatives thereof | SEARLE & CO (US) | 1994-03-30 | — | — | EP | claimed |
| US-5990326-A | AN ANTIINFLAMMATORY AGENT AS INHIBITORS OF LEUKOTRIENE HYDROLASE | G.D. SEARLE & CO. (US) | 1999-11-23 | — | — | US | disclosed |
| EP-0360246-B1 | 3-Oxiranyl benzoic acids and derivatives thereof | SEARLE & CO (US) | 1994-03-30 | — | — | EP | disclosed |
| EP-0360246-A1 | 3-Oxiranyl benzoic acids and derivatives thereof | G.D. Searle & Co. (US) | 1990-03-28 | — | — | EP | disclosed |