Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.31 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417941 | 0.91 | PPARG (0.35) | AGTR1AGTR2 | |
| SCHEMBL8417984 | 0.89 | AGTR1 (0.34) | AGTR1AGTR2 | |
| SCHEMBL8421429 | 0.88 | AGTR1 (0.34) | AGTR1AGTR2 | |
| SCHEMBL8635491 | 0.86 | DHODH (0.35) | DHODHAGTR1AGTR2 | |
| SCHEMBL8419217 | 0.86 | AGTR1 (0.33) | DHODHAGTR1 | |
| SCHEMBL8421698 | 0.84 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL8418024 | 0.83 | ALDH1A1 (0.36) | AGTR1AGTR2 | |
| SCHEMBL8422151 | 0.83 | DHODH (0.35) | DHODHAGTR1AGTR2 | |
| SCHEMBL8419127 | 0.83 | AGTR1 (0.34) | AGTR1AGTR2 | |
| SCHEMBL8519654 | 0.83 | AGTR1 (0.33) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962491-A | ANGIOTENSIN ANTAGONIST, HYPOTENSIVE AGENTS, CARDIOVASCULAR DISORDERS, STROKES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5705517-A | ANGIOTENSIN II ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-01-06 | — | — | US | disclosed |
| US-5703110-A | HYPOTENSIVE AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-12-30 | — | — | US | disclosed |