SCHEMBL8419211

SCHEMBL8419211

C=CCn1c(OC2CCCS2)n[nH]c1=O

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
APOBEC3G Q9HC16 1/20 0.33
NPC1 O15118 1/20 0.33
S1PR4 O95977 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
S1PR1 P21453 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TLR9 Q9NR96 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8505340 0.70 GAA (0.42) KDM4EAPOBEC3GNPC1S1PR4ALDH1A1
SCHEMBL5391863 0.63 CYP3A4 (0.46) KDM4EAPOBEC3GNPC1S1PR4ALDH1A1
SCHEMBL7546639 0.63 APOBEC3G (0.39) APOBEC3GNPC1S1PR4ALDH1A1MAPT
SCHEMBL7763858 0.62 CYP3A4 (0.45) KDM4EAPOBEC3GNPC1S1PR4ALDH1A1
SCHEMBL5391867 0.62 CYP3A4 (0.45) KDM4EAPOBEC3GNPC1S1PR4ALDH1A1
SCHEMBL3584589 0.60 ADORA2B (0.42) KDM4EAPOBEC3GNPC1S1PR4ALDH1A1
SCHEMBL21853415 0.60 CYP3A4 (0.42) KDM4EAPOBEC3GNPC1S1PR4ALDH1A1
SCHEMBL9413995 0.59 ALDH1A1 (0.48) KDM4ENPC1S1PR4ALDH1A1MAPT
SCHEMBL4233131 0.58
SCHEMBL16324350 0.58 LMNA (0.33) KDM4ENPC1ALDH1A1MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6001776-A FOR THE SELECTIVE COMBATING OF MONOCOTYLEDON AND DICOTYLEDON WEEDS IN MONOCOTYLEDON AND DICOTYLEDON CROPS, BOTH PRE-EMERGENCE AND POST-EMERGENCE BAYER AKTIENGESELLSCHAFT (DE) 1999-12-14 US disclosed