Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.37 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421753 | 0.87 | PTGER2 (0.47) | EPHX2PTGER2ALDH1A1KMT2A | |
| SCHEMBL8421751 | 0.85 | EPHX2 (0.37) | EPHX2SPHK1ALDH1A1KMT2ACYP4F2 | |
| SCHEMBL8419637 | 0.85 | EPHX2 (0.37) | EPHX2SPHK1SPHK2ALDH1A1KMT2A | |
| SCHEMBL8421824 | 0.84 | EPHX2 (0.36) | EPHX2ALDH1A1KMT2A | |
| SCHEMBL8419697 | 0.84 | EPHX2 (0.38) | EPHX2ALDH1A1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL9237067 | 0.84 | CA12 (0.42) | EPHX2ALDH1A1 | |
| SCHEMBL8419602 | 0.82 | EPHX2 (0.36) | EPHX2SPHK1SPHK2ALDH1A1KMT2A | |
| SCHEMBL8421136 | 0.82 | ALDH1A1 (0.37) | EPHX2PTGER2ALDH1A1KMT2ACYP4F2 | |
| SCHEMBL9236137 | 0.81 | HDAC3 (0.43) | EPHX2 | |
| SCHEMBL8421488 | 0.81 | FAAH (0.39) | EPHX2S1PR2S1PR1S1PR3SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943606-A1 | BENZENESULFONAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME | HOKURIKU SEIYAKU CO., LTD. (JP) | 1999-09-22 | — | — | EP | disclosed |