Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PTPRB | P23467 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421824 | 0.92 | EPHX2 (0.36) | EPHX2PTPRBALDH1A1KMT2AADRB2 | |
| SCHEMBL8419697 | 0.92 | EPHX2 (0.38) | EPHX2PTPRBALDH1A1KMT2AADRB2 | |
| SCHEMBL8421751 | 0.91 | EPHX2 (0.37) | EPHX2PTPRBALDH1A1KMT2AADRB2 | |
| SCHEMBL8419602 | 0.89 | EPHX2 (0.36) | EPHX2PTPRBALDH1A1KMT2AADRB2 | |
| SCHEMBL8421488 | 0.88 | FAAH (0.39) | EPHX2MLYCDSPHK1SPHK2 | |
| SCHEMBL8421772 | 0.88 | PTGER2 (0.43) | EPHX2ALDH1A1KMT2AADRB2ADRB1 | |
| SCHEMBL8419326 | 0.86 | EPHX2 (0.36) | EPHX2PTPRBALDH1A1KMT2AADRB2 | |
| SCHEMBL8419503 | 0.85 | EPHX2 (0.38) | EPHX2ALDH1A1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL8421474 | 0.85 | EPHX2 (0.35) | EPHX2PTPRBALDH1A1KMT2AADRB2 | |
| SCHEMBL8421136 | 0.85 | ALDH1A1 (0.37) | EPHX2PTPRBALDH1A1KMT2AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943606-A1 | BENZENESULFONAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME | HOKURIKU SEIYAKU CO., LTD. (JP) | 1999-09-22 | — | — | EP | disclosed |