Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28319606 | 0.93 | ALDH1A1 (0.43) | ALDH1A1TP53TSHRCA1CA2 | |
| SCHEMBL5855950 | 0.85 | TSHR (0.38) | ALDH1A1TP53TSHR | |
| SCHEMBL1771607 | 0.82 | ALDH1A1 (0.39) | ALDH1A1TP53TSHR | |
| SCHEMBL3971918 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TP53TSHR | |
| SCHEMBL865735 | 0.78 | CA1 (0.35) | CA1CA2MEN1KMT2A | |
| SCHEMBL865736 | 0.78 | LMNA (0.48) | ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL8593427 | 0.77 | ALDH1A1 (0.42) | ALDH1A1TP53TSHRCA1CA2 | |
| SCHEMBL9438220 | 0.74 | TSHR (0.41) | ALDH1A1TP53TSHR | |
| SCHEMBL23303403 | 0.73 | ALDH1A1 (0.46) | ALDH1A1TP53TSHRMEN1KMT2A | |
| SCHEMBL10442040 | 0.71 | TSHR (0.50) | ALDH1A1TP53TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943606-A1 | BENZENESULFONAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME | HOKURIKU SEIYAKU CO., LTD. (JP) | 1999-09-22 | — | — | EP | disclosed |