Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9438220 | 0.89 | TSHR (0.41) | TSHRALDH1A1TP53 | |
| SCHEMBL8419645 | 0.85 | ALDH1A1 (0.42) | TSHRALDH1A1TP53 | |
| SCHEMBL1727128 | 0.85 | TSHR (0.35) | TSHRALDH1A1TP53 | |
| SCHEMBL9438217 | 0.84 | TSHR (0.38) | TSHRALDH1A1TP53 | |
| SCHEMBL28319606 | 0.83 | ALDH1A1 (0.43) | TSHRALDH1A1TP53 | |
| SCHEMBL1727544 | 0.83 | THRB (0.34) | TSHRALDH1A1TP53 | |
| SCHEMBL9438164 | 0.82 | TSHR (0.36) | TSHRALDH1A1TP53 | |
| SCHEMBL23294783 | 0.81 | THRB (0.38) | TSHRALDH1A1TP53 | |
| SCHEMBL3964350 | 0.81 | THRB (0.38) | TSHRALDH1A1TP53 | |
| SCHEMBL3695200 | 0.80 | TSHR (0.35) | TSHRALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023284-B | Calixarene compound and curable composition | DIC株式会社 | 2022-01-18 | — | — | CN | disclosed |
| US-11111225-B2 | Calixarene compound and curable composition | DIC CORPORATION (JP) | 2021-09-07 | — | — | US | disclosed |
| US-20190276421-A1 | CALIXARENE COMPOUND AND CURABLE COMPOSITION | DIC CORPORATION (JP) | 2019-09-12 | — | — | US | disclosed |
| US-7074819-B2 | Benzopyran or thiobenzopyran derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2006-07-11 | — | — | US | disclosed |
| US-20040102479-A1 | Novel benzopyran or thiobenzopyran derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA | 2004-05-27 | — | — | US | disclosed |
| US-6645951-B1 | Antiestrogens for treating breast cancer | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-11-11 | — | — | US | disclosed |
| EP-1087959-A1 | NOVEL BENZOPYRAN OR THIOBENZOPYRAN DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065893-A1 | NOVEL BENZOPYRAN OR THIOBENZOPYRAN DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 1999-12-23 | — | — | WO | disclosed |
| US-4085099-A | AZO DYES | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1978-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102479-A1 | Novel benzopyran or thiobenzopyran derivatives | NR5A1, SHBG, ESR2 | TSHR 520/4885ALDH1A1 453/4885TP53 3309/4885 |
| US-20190276421-A1 | CALIXARENE COMPOUND AND CURABLE COMPOSITION | CALU, CALCRL, CAPN1 | TSHR 1059/4885ALDH1A1 1469/4885TP53 2950/4885 |
| US-11111225-B2 | Calixarene compound and curable composition | CALU, CALCRL, CAPN1 | TSHR 1059/4885ALDH1A1 1469/4885TP53 2950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.