Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 12/20 | 0.35 |
| ▸ | PLG | P00747 | 10/20 | 0.35 |
| ▸ | F2 | P00734 | 7/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 11/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 11/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 11/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420031 | 0.84 | FDFT1 (0.42) | FDFT1F10PLGF2PRSS1 | |
| SCHEMBL8419759 | 0.82 | FDFT1 (0.44) | FDFT1F10PLGF2PRSS1 | |
| SCHEMBL8919905 | 0.82 | FDFT1 (0.41) | FDFT1 | |
| SCHEMBL8419678 | 0.82 | FDFT1 (0.39) | FDFT1F10PLGF2PRSS1 | |
| SCHEMBL8419593 | 0.80 | FDFT1 (0.49) | FDFT1 | |
| SCHEMBL8419647 | 0.80 | — | — | |
| SCHEMBL8420486 | 0.79 | FDFT1 (0.43) | FDFT1LMNACYP3A4KDM4E | |
| SCHEMBL8417632 | 0.79 | FDFT1 (0.60) | FDFT1 | |
| SCHEMBL8420062 | 0.78 | FDFT1 (0.47) | FDFT1 | |
| SCHEMBL8419682 | 0.78 | FDFT1 (0.46) | FDFT1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919793-A | QUINUCLIDINE DERIVATIVES, SQUALENE SYNTHETASE INHIBITORS, ANTICHOLESTEROL AGENTS | ZENECA LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |