Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417805 | 0.91 | FDFT1 (0.35) | FDFT1ALDH1A1OPRD1HTTRAB9A | |
| SCHEMBL8419678 | 0.89 | FDFT1 (0.39) | FDFT1ALDH1A1OPRD1SMN1; SMN2MAPK1 | |
| SCHEMBL8417907 | 0.89 | PHLPP2 (0.35) | FDFT1ALDH1A1TDP1POLBMAPK1 | |
| SCHEMBL8918777 | 0.88 | TDP1 (0.37) | FDFT1ALDH1A1TDP1POLBGAA | |
| SCHEMBL8920428 | 0.87 | ALDH1A1 (0.36) | FDFT1ALDH1A1OPRD1HTTHPGD | |
| SCHEMBL8419759 | 0.84 | FDFT1 (0.44) | FDFT1ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL8420062 | 0.83 | FDFT1 (0.47) | FDFT1 | |
| SCHEMBL8919982 | 0.79 | MMP13 (0.46) | FDFT1ALDH1A1TDP1POLBGAA | |
| SCHEMBL8421874 | 0.79 | FDFT1 (0.39) | FDFT1 | |
| SCHEMBL8921229 | 0.77 | ATM (0.43) | ALDH1A1POLBSMN1; SMN2MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691349-A | ANTICHOLESTEROL AGENTS; ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 1997-11-25 | — | — | US | claimed |
| US-5691349-A | ANTICHOLESTEROL AGENTS; ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 1997-11-25 | — | — | US | disclosed |