Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP8 | P22894 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | F2 | P00734 | 2/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31251161 | 0.85 | KMT2A (0.70) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL2184509 | 0.85 | KMT2A (0.70) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL11566827 | 0.80 | KMT2A (1.00) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL2039879 | 0.80 | KMT2A (1.00) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL30446303 | 0.80 | KMT2A (1.00) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL237684 | 0.78 | KMT2A (0.73) | KMT2AMEN1CA1CA2MMP1 | |
| Zinc Ion SCHEMBL4580866 | 0.77 | KMT2A (0.70) | KMT2AMEN1CA1CA2MMP1 | |
| Potassium Ion SCHEMBL7460752 | 0.77 | KMT2A (0.70) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL1148394 | 0.77 | KMT2A (0.70) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL17278 | 0.77 | KMT2A (0.70) | KMT2AMEN1CA1CA2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784614-B1 | THE PREPARATION OF FLUORINATED ORGANIC COMPOUNDS | F2 CHEMICALS LIMITED (GB) | 1999-10-06 | — | — | EP | disclosed |
| US-5741935-A | Preparation of organic pentafluorosulphur compounds | BRITISH NUCLEAR FUELS PLC (GB) | 1998-04-21 | — | — | US | disclosed |
| EP-0784614-A1 | THE PREPARATION OF FLUORINATED ORGANIC COMPOUNDS | British Nuclear Fuels PLC (GB) | 1997-07-23 | — | — | EP | disclosed |
| WO-1997005106-A1 | THE PREPARATION OF FLUORINATED ORGANIC COMPOUNDS | BRITISH NUCLEAR FUELS PLC (GB) | 1997-02-13 | — | — | WO | disclosed |