Sugi Predict

Sugi Predict / Compounds / SCHEMBL1148394

SCHEMBL1148394

SCHEMBL1148394

O=[N+]([O-])c1ccccc1S(=O)(=O)Br

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 5/20 0.70
▸ MEN1 O00255 4/20 0.70
▸ CA1 P00915 1/20 0.59
▸ CA2 P00918 1/20 0.59
▸ MMP1 P03956 1/20 0.59
▸ MMP2 P08253 1/20 0.59
▸ MMP9 P14780 1/20 0.59
▸ MMP8 P22894 1/20 0.59
▸ MMP13 P45452 1/20 0.59
▸ F2 P00734 3/20 0.54
▸ PRSS1 P07477 3/20 0.54
▸ PRSS2 P07478 3/20 0.54
▸ PRSS3 P35030 3/20 0.54
▸ ALDH1A1 P00352 2/20 0.53
▸ THRB P10828 1/20 0.50
▸ CYP19A1 P11511 1/20 0.49
▸ PKM P14618 1/20 0.49
▸ TDP1 Q9NUW8 1/20 0.47
▸ ACHE P22303 1/20 0.47
▸ LMNA P02545 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30026176 1.00 KMT2A (0.70) KMT2AMEN1CA1CA2MMP1
SCHEMBL2039879 0.83 KMT2A (1.00) KMT2AMEN1CA1CA2MMP1
SCHEMBL30446303 0.83 KMT2A (1.00) KMT2AMEN1CA1CA2MMP1
SCHEMBL11566827 0.83 KMT2A (1.00) KMT2AMEN1CA1CA2MMP1
SCHEMBL29849759 0.82 KMT2A (0.53) KMT2AMEN1CA1CA2MMP1
SCHEMBL31294234 0.82 KMT2A (0.53) KMT2AMEN1CA1CA2MMP1
SCHEMBL237684 0.81 KMT2A (0.73) KMT2AMEN1CA1CA2MMP1
Potassium Ion SCHEMBL7460752 0.79 KMT2A (0.70) KMT2AMEN1CA1CA2MMP1
SCHEMBL2913624 0.79 KMT2A (0.70) KMT2AMEN1CA1CA2MMP1
SCHEMBL2184509 0.79 KMT2A (0.70) KMT2AMEN1CA1CA2MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3854786-B1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES UBE CORP (JP) 2026-02-18 — — EP disclosed
US-12281074-B2 Method for producing amino acid derivatives UBE CORPORATION (JP) 2025-04-22 — — US disclosed
CN-119707784-A Process for preparing amino acid derivatives 株式会社API 2025-03-28 — — CN disclosed
US-12202800-B2 Method for producing amino acid derivatives API CORPORATION (JP) 2025-01-21 — — US disclosed
CN-112930338-B Process for preparing amino acid derivatives 株式会社API 2024-12-24 — — CN disclosed
US-20240150292-A1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES API CORPORATION (JP) 2024-05-09 — — US disclosed
US-20240084102-A1 BISDIAMINOPHENYL COMPOUND, CROSSLINKING AGENT, COMPOSITION, AND MOLDED ARTICLE DAIKIN INDUSTRIES, LTD. (JP) 2024-03-14 — — US disclosed
EP-4324821-A1 BISDIAMINOPHENYL COMPOUND, CROSSLINKING AGENT, COMPOSITION, AND MOLDED ARTICLE DAIKIN INDUSTRIES, LTD. (JP) 2024-02-21 — — EP disclosed
US-11897844-B2 Method for producing amino acid derivatives API CORPORATION (JP) 2024-02-13 — — US disclosed
US-20240002340-A1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES API CORPORATION (JP) 2024-01-04 — — US disclosed
US-8481744-B2 Process for producing anthranilamide compound ISHIHARA SANGYO KAISHA, LTD. (JP) 2013-07-09 — — US disclosed
EP-2264021-B1 PROCESS FOR PRODUCING AN ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA (JP) 2013-06-26 — — EP disclosed
US-20110034696-A1 PROCESS FOR PRODUCING ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA, LTD. (JP) 2011-02-10 — — US disclosed
EP-2264021-A1 PROCESS FOR PRODUCING AN ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-12-22 — — EP disclosed
EP-0934928-B1 CYCLIC AMINE DERIVATIVES SANKYO CO (JP) 2004-10-13 — — EP disclosed
US-6610708-B1 Anticoagulants SANKYO COMPANY, LIMITED (JP) 2003-08-26 — — US disclosed
EP-1063230-B1 CYCLIC AMINO COMPOUNDS SANKYO CO (JP) 2003-04-23 — — EP disclosed
EP-1063230-A1 CYCLIC AMINO COMPOUNDS Sankyo Company Limited (JP) 2000-12-27 — — EP disclosed
US-6087379-A AN ANTICOAGULANT FOR THE TREATMENT AND PREVENTION OF DISEASES AS EMBOLISM, THROMBOSIS OR ARTERIOSCLEROSIS SANKYO COMPANY, LIMITED (JP) 2000-07-11 — — US disclosed
EP-0934928-A1 CYCLIC AMINE DERIVATIVES SANKYO COMPANY LIMITED (JP) 1999-08-11 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240084102-A1 BISDIAMINOPHENYL COMPOUND, CROSSLINKING AGENT, COMPOSITION, AND MOLDED ARTICLE PAH, AHR, ARSA KMT2A 450/4885MEN1 700/4885CA1 2984/4885
US-20110034696-A1 PROCESS FOR PRODUCING ANTHRANILAMIDE COMPOUND SQOR, NOX5, NOX3 KMT2A 773/4885MEN1 3668/4885CA1 1161/4885
US-20240150292-A1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES PTGS2, PTGES, PTGS1 KMT2A 1072/4885MEN1 3926/4885CA1 3133/4885
US-12202800-B2 Method for producing amino acid derivatives GLO1, BCAT2, BCAT1 KMT2A 2383/4885MEN1 1823/4885CA1 612/4885
US-20240002340-A1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES GLO1, BCAT2, BCAT1 KMT2A 2383/4885MEN1 1823/4885CA1 612/4885
US-11897844-B2 Method for producing amino acid derivatives PTGS2, PTGES, PTGES2 KMT2A 1086/4885MEN1 4008/4885CA1 3249/4885
US-12281074-B2 Method for producing amino acid derivatives PTGS2, PTGES, PTGES2 KMT2A 1086/4885MEN1 4008/4885CA1 3249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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