Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | MMP1 | P03956 | 1/20 | 0.59 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | MMP8 | P22894 | 1/20 | 0.59 |
| ▸ | MMP13 | P45452 | 1/20 | 0.59 |
| ▸ | F2 | P00734 | 3/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.59 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.59 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL31590411 | 1.00 | KMT2A (0.70) | KMT2AMEN1CA1CA2MMP1 | |
| Lithium Ion SCHEMBL28617228 | 0.96 | KMT2A (0.70) | KMT2AMEN1CA1CA2MMP1 | |
| Silver SCHEMBL28472363 | 0.96 | KMT2A (0.70) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL176928 | 0.96 | KMT2A (0.70) | KMT2AMEN1CA1CA2MMP1 | |
| Zinc Ion SCHEMBL4580866 | 0.96 | KMT2A (0.70) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL31348020 | 0.96 | KMT2A (0.70) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL1926677 | 0.96 | KMT2A (0.70) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL30019896 | 0.96 | KMT2A (0.70) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL8402996 | 0.96 | KMT2A (0.70) | KMT2AMEN1CA1CA2MMP1 | |
| Water SCHEMBL30398921 | 0.94 | KMT2A (0.68) | KMT2AMEN1CA1CA2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6427599-B1 | AUTOMOBILE AIR BAGS; DECOY FLARES | BAE SYSTEMS INTEGRATED DEFENSE SOLUTIONS INC. | 2002-08-06 | — | — | US | disclosed |
| EP-0345550-A2 | High molecular weight arylene sulphide polymers | BAYER AG (DE) | 1989-12-13 | — | — | EP | disclosed |