Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | PPIA | P62937 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68180 | 0.81 | MAPT (0.70) | GAAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11849929 | 0.81 | GAA (0.61) | GAAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11542953 | 0.80 | ALDH1A1 (0.67) | GAAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL6155867 | 0.79 | IDO1 (0.72) | GAAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL30149489 | 0.79 | GAA (0.77) | GAAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL18286554 | 0.78 | GAA (0.57) | GAAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL1083471 | 0.77 | SMN1; SMN2 (0.65) | GAAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL30577265 | 0.77 | SMN1; SMN2 (0.81) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL6811589 | 0.76 | ALDH1A1 (0.62) | GAAALDH1A1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL11158946 | 0.76 | SMN1; SMN2 (0.63) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877324-A | ANTICHOLESTEROL AGENT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-03-02 | — | — | US | disclosed |