Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.64 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 5/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | CETP | P11597 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8056967 | 0.80 | AR (0.72) | ARALDH1A1ALOX5HPGDGAA | |
| SCHEMBL17009411 | 0.79 | AR (1.00) | ARALDH1A1ALOX5HPGDGAA | |
| SCHEMBL7062983 | 0.78 | ALDH1A1 (1.00) | ARALDH1A1ALOX5HPGDGAA | |
| SCHEMBL8823050 | 0.78 | ALDH1A1 (0.79) | ARALDH1A1ALOX5HPGDGAA | |
| SCHEMBL17014756 | 0.76 | AR (1.00) | ARALDH1A1ALOX5HPGDGAA | |
| SCHEMBL27484530 | 0.75 | ALDH1A1 (0.67) | ARALDH1A1ALOX5HPGDGAA | |
| SCHEMBL17014808 | 0.74 | ALDH1A1 (0.71) | ARALDH1A1ALOX5HPGDGAA | |
| SCHEMBL5806903 | 0.71 | AR (0.55) | ARALDH1A1ALOX5HPGDGAA | |
| SCHEMBL15978869 | 0.69 | AR (0.56) | ARALDH1A1ALOX5HPGDGAA | |
| SCHEMBL1304512 | 0.68 | CETP (0.74) | ARALDH1A1ALOX5HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0941990-A2 | Process for the preparation of azamethines and azamethines obtained thereby | SIEMENS AKTIENGESELLSCHAFT (DE) | 1999-09-15 | — | — | EP | disclosed |