Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | CETP | P11597 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17009411 | 0.84 | AR (1.00) | ARALDH1A1ALOX5GAAHPGD | |
| SCHEMBL9548136 | 0.83 | KMT2A (0.74) | ARALDH1A1GAAHPGDPTGS2 | |
| SCHEMBL8823050 | 0.83 | ALDH1A1 (0.79) | ARALDH1A1ALOX5GAAHPGD | |
| SCHEMBL5806903 | 0.80 | AR (0.55) | ARALDH1A1ALOX5GAAHPGD | |
| SCHEMBL8419989 | 0.80 | AR (0.65) | ARALDH1A1ALOX5GAAHPGD | |
| SCHEMBL17014756 | 0.80 | AR (1.00) | ARALDH1A1ALOX5GAAHPGD | |
| SCHEMBL7062983 | 0.80 | ALDH1A1 (1.00) | ARALDH1A1ALOX5GAAHPGD | |
| SCHEMBL12491446 | 0.79 | AR (0.50) | ARALDH1A1ALOX5GAAHPGD | |
| SCHEMBL17014808 | 0.78 | ALDH1A1 (0.71) | ARALDH1A1ALOX5GAAHPGD | |
| SCHEMBL27048230 | 0.77 | ALDH1A1 (0.53) | ARALDH1A1ALOX5PTGS2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592664-B1 | DERIVATIVES OF DIPHENYLTHIAZOLE WITH ANTIINFLAMMATORY ACTIVITY | HISAMITSU PHARMACEUTICAL CO (JP) | 2000-07-05 | — | — | EP | disclosed |
| US-5449783-A | Antiinflammatory, analgesic, antiallergic, diuretic agents, anticoagulants | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1995-09-12 | — | — | US | disclosed |
| EP-0592664-A1 | NOVEL DIPHENYLTHYAZOLE DERIVATIVE | Hisamitsu Pharmaceutical Co., Inc. (JP) | 1994-04-20 | — | — | EP | disclosed |