SCHEMBL842004

SCHEMBL842004

Cc1cccc(C(N)=O)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl

nearest known ligand 0.70

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 3/20 0.51
CHRNA7 P36544 8/20 0.38
MALT1 Q9UDY8 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.37
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37
RAB9A P51151 1/20 0.37
LCK P06239 4/20 0.36
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31060097 0.90 DHODH (0.44) DHODHMALT1SMN1; SMN2ALDH1A1HPGD
SCHEMBL15984455 0.90 DHODH (0.44) DHODHMALT1SMN1; SMN2ALDH1A1HPGD
SCHEMBL29377193 0.90 DHODH (0.44) DHODHMALT1SMN1; SMN2ALDH1A1HPGD
SCHEMBL16563751 0.89 DHODH (0.48) DHODHCHRNA7MALT1SMN1; SMN2LCK
SCHEMBL31060076 0.88 DHODH (0.45) DHODHCHRNA7MALT1SMN1; SMN2ALDH1A1
SCHEMBL12911683 0.88 DHODH (0.49) DHODHCHRNA7MALT1SMN1; SMN2LCK
SCHEMBL3086322 0.88 DHODH (0.49) DHODHCHRNA7MALT1SMN1; SMN2LCK
SCHEMBL25229450 0.87 DHODH (0.44) DHODHMALT1MAPT
SCHEMBL3200941 0.87 DHODH (0.49) DHODHCHRNA7MALT1SMN1; SMN2ALDH1A1
SCHEMBL13318558 0.87 DHODH (0.48) DHODHCHRNA7MALT1SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8143292-B2 N-Thio-anthranilamid compounds and their use as pesticides BASF SE (DE) 2012-03-27 US disclosed
EP-1904475-B1 N-THIO-ANTHRANILAMID COMPOUNDS AND THEIR USE AS PESTICIDES BASF SE (DE) 2011-08-17 EP disclosed