Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.34 |
| ▸ | F2R | P25116 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3086322 | 0.88 | DHODH (0.49) | DHODHMAPK14CHRNA7MALT1LCK | |
| SCHEMBL842004 | 0.87 | DHODH (0.51) | DHODHCHRNA7MALT1LCKSMN1; SMN2 | |
| SCHEMBL12911683 | 0.84 | DHODH (0.49) | DHODHCHRNA7MALT1LCKSMN1; SMN2 | |
| SCHEMBL16564047 | 0.84 | DHODH (0.51) | DHODHMAPK14MALT1LCKSMN1; SMN2 | |
| SCHEMBL13318558 | 0.83 | DHODH (0.48) | DHODHCHRNA7MALT1LCKSMN1; SMN2 | |
| SCHEMBL16563751 | 0.83 | DHODH (0.48) | DHODHCHRNA7MALT1LCKSMN1; SMN2 | |
| SCHEMBL28633768 | 0.82 | DHODH (0.45) | DHODHCHRNA7MALT1LCKMAPT | |
| SCHEMBL16573264 | 0.81 | DHODH (0.49) | DHODHMAPK14CHRNA7MALT1LCK | |
| SCHEMBL28641754 | 0.81 | DHODH (0.45) | DHODHCHRNA7TP53ALDH1A1 | |
| SCHEMBL28645998 | 0.80 | DHODH (0.44) | DHODHCHRNA7MALT1LCKTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7674936-B2 | Ortho-substituted aryl amides for controlling invertebrate pests | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-03-09 | — | — | US | disclosed |
| EP-1423379-B1 | ORTHO-SUBSTITUTED ARYL AMIDES FOR CONTROLLING INVERTEBRATE PESTS | DU PONT (US) | 2008-05-28 | — | — | EP | disclosed |
| US-7288554-B2 | Ortho-substituted aryl amides for controlling invertebrate pests | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-10-30 | — | — | US | disclosed |
| US-20070249832-A1 | Ortho-substituted aryl amides for controlling invertebrate pests | FMC CORPORATION | 2007-10-25 | — | — | US | disclosed |
| US-20040192731-A1 | Ortho-substituted aryl amides for controlling invertebrate pests | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192731-A1 | Ortho-substituted aryl amides for controlling invertebrate pests | DDT, ACHE, CBR1 | DHODH 2531/4885MAPK14 1980/4885CHRNA7 1884/4885 |
| US-20070249832-A1 | Ortho-substituted aryl amides for controlling invertebrate pests | NR2C2, GRK6, NR0B2 | DHODH 3663/4885MAPK14 3190/4885CHRNA7 538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.