Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.52 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.52 |
| ▸ | PPARD | Q03181 | 3/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | AGER | Q15109 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27438031 | 0.81 | ELANE (0.39) | PTGDR2PTGDRPTPN1ALDH1A1MEN1 | |
| SCHEMBL27460919 | 0.80 | MEN1 (0.38) | PTGDR2PTGDRALDH1A1MEN1KMT2A | |
| SCHEMBL8420019 | 0.79 | KDM4E (0.39) | PTGDR2PTGDRALDH1A1TSHRMEN1 | |
| SCHEMBL8417976 | 0.79 | PPARA (0.42) | PTGDR2PTGDRPPARD | |
| SCHEMBL8971311 | 0.79 | PTGDR (0.38) | PTGDR2PTGDRALDH1A1MEN1KMT2A | |
| SCHEMBL8969386 | 0.77 | PPARA (0.46) | PTGDR2PTGDRPPARDHSD17B10 | |
| SCHEMBL8969655 | 0.76 | PTGDR (0.38) | PTGDR2PTGDRALDH1A1TSHRMEN1 | |
| SCHEMBL4771232 | 0.76 | ELANE (0.46) | PTGDR2PTGDRPTPN1ALDH1A1MEN1 | |
| SCHEMBL9432238 | 0.76 | PPARA (0.47) | PTGDR2PTGDRPPARDMAPT | |
| SCHEMBL8418498 | 0.75 | PTGS2 (0.43) | PTGDR2PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919793-A | QUINUCLIDINE DERIVATIVES, SQUALENE SYNTHETASE INHIBITORS, ANTICHOLESTEROL AGENTS | ZENECA LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025459-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |