Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9432238 | 0.97 | PPARA (0.47) | PPARAPPARGPTGDRPTGDR2CYP1A2 | |
| SCHEMBL8417976 | 0.93 | PPARA (0.42) | PPARAPTGDRPTGDR2PPARDALOX5 | |
| SCHEMBL8419852 | 0.89 | PPARA (0.40) | PPARAPPARGPPARDALOX5 | |
| SCHEMBL8969517 | 0.87 | CYP4Z1 (0.40) | PPARAALOX5MAPK1SMN1; SMN2AKR1C3 | |
| SCHEMBL8419836 | 0.86 | ALOX5 (0.41) | PPARAPTGDRPTGDR2CYP1A2PPARD | |
| SCHEMBL8417735 | 0.86 | PTGDR (0.39) | PPARAPTGDRPTGDR2PPARDALOX5 | |
| SCHEMBL8419978 | 0.86 | PPARA (0.42) | PPARAPPARGPPARDALOX5 | |
| SCHEMBL27436177 | 0.86 | PPARA (0.39) | PPARAPPARGPTGDRPTGDR2CYP1A2 | |
| SCHEMBL8421859 | 0.85 | PPARA (0.41) | PPARAPPARGPPARDALOX5 | |
| SCHEMBL27460107 | 0.84 | APP (0.44) | PPARAPTGDRPTGDR2PPARDALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025459-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |