SCHEMBL842024

SCHEMBL842024

C[Si](C)(N[Si](C)(C)c1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
NPC1 O15118 4/20 0.36
RAB9A P51151 4/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
TSHR P16473 2/20 0.35
CA4 P22748 1/20 0.35
NR1H2 P55055 2/20 0.34
NR1H3 Q13133 2/20 0.34
HPGD P15428 2/20 0.33
LMNA P02545 1/20 0.33
ALOX12 P18054 1/20 0.33
ACHE P22303 1/20 0.33
POLB P06746 1/20 0.33
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
MAPT P10636 1/20 0.33
ELANE P08246 2/20 0.32
ALDH1A1 P00352 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16860017 0.89 ESR1 (0.39) ESR1ESR2TSHRCA4NR1H2
SCHEMBL29757964 0.87 ESR1 (0.38) ESR1ESR2NPC1RAB9ASMN1; SMN2
SCHEMBL7894540 0.81 ESR1 (0.34) ESR1ESR2CA4MAPTKCNN4
SCHEMBL2275514 0.80 ESR1 (0.41) ESR1ESR2TSHRCA4NR1H2
SCHEMBL4949411 0.78
SCHEMBL4577783 0.78 ESR1 (0.39) ESR1ESR2TSHRCA4NR1H2
SCHEMBL7037975 0.78 ESR1 (0.39) ESR1ESR2TSHRCA4NR1H2
SCHEMBL842862 0.77 ESR1 (0.42) ESR1ESR2NPC1RAB9ASMN1; SMN2
SCHEMBL2273250 0.76 ESR1 (0.38) ESR1ESR2NPC1RAB9ASMN1; SMN2
SCHEMBL3152396 0.76 ESR1 (0.38) ESR1ESR2TSHRCA4NR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 484 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260098105-A1 PREPOLYMERIZED CATALYST FOR OLEFIN POLYMERIZATION, METHOD OF PRODUCING THIS PREPOLYMERIZED CATALYST AND METHOD OF PRODUCING OLEFIN POLYMER WITH IMPROVED PROCESSABILITY AND OPTICAL PROPERTIES FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2026-04-09 US claimed
WO-2025106343-A1 ETCHING METHODS FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2025-05-22 WO claimed
CN-119685000-A Modified perovskite quantum dot and preparation method thereof 极电光能有限公司 2025-03-25 CN claimed
CN-119612540-A ZSM-5 molecular sieve and preparation and application thereof 中国石油化工股份有限公司 2025-03-14 CN claimed
CN-115895546-B Thermosetting resin composition and insulating adhesive film thereof 广东生益科技股份有限公司 2025-01-07 CN claimed
CN-117106483-B Residual oil hydrogenation anti-coking scale inhibitor and preparation method thereof 江苏创新石化有限公司 2024-12-17 CN claimed
CN-110462525-B Surface treatment method and composition for use in the method 富士胶片电子材料美国有限公司 2024-07-26 CN claimed
CN-118344845-A Surface treatment method and composition for use in the method 富士胶片电子材料美国有限公司 2024-07-16 CN claimed
CN-117106483-A Residual oil hydrogenation anti-coking scale inhibitor and preparation method thereof 江苏创新石化有限公司 2023-11-24 CN claimed
CN-115895546-A Thermosetting resin composition and insulating adhesive film thereof 广东生益科技股份有限公司 2023-04-04 CN claimed
US-6946538-B2 Catalyst for isocyanate condensation, composition containing same, method for use, and resulting compositions RHODIA CHIMIE (FR) 2005-09-20 US claimed
US-6875243-B2 Catalysts for preparing polyisocyanates containing isocyanurate groups, and their use DEGUSSA AG (DE) 2005-04-05 US claimed
CN-1484660-A Catal yst for isocyanate condensation composition containing same method for usse and resulting compositions �޵��ǻ�ѧ��˾ 2004-03-24 CN claimed
US-20040024212-A1 Catalyst for isocyanate condensation, composition containing same, method for use, and resulting compositions VENCOREX FRANCE (FR) 2004-02-05 US claimed
US-20030109665-A1 Catalysts for preparing polyisocyanates containing isocyanurate groups, and their use DEGUSSA AG (DE) 2003-06-12 US claimed
EP-1318152-A2 Catalysts and process for preparing polyisocyanates containing isocyanurate groups and their use Degussa AG (DE) 2003-06-11 EP claimed
EP-1318160-A1 Catalysts and process for the preparation of isocyanurate group containing polyisocyanates and their use Degussa AG (DE) 2003-06-11 EP claimed
US-6365643-B1 Photoinitiators for cationic curing TH. GOLDSCHMIDT AG (DE) 2002-04-02 US claimed
WO-1995020613-A1 POLYMERISATION OF CYCLOALKENES UNIVERSITE LAVAL (CA) 1995-08-03 WO claimed
US-4412073-A Isocyanurate preparation by catalytic, aminosilyl initiated cyclotrimerization of isocyanates RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1983-10-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260098105-A1 PREPOLYMERIZED CATALYST FOR OLEFIN POLYMERIZATION, METHOD OF PRODUCING THIS PREPOLYMERIZED CATALYST AND METHOD OF PRODUCING OLEFIN POLYMER WITH IMPROVED PROCESSABILITY AND OPTICAL PROPERTIES DIS3, DRD4, SRP54 ESR1 1506/4885ESR2 2465/4885NPC1 2617/4885
US-20040024212-A1 Catalyst for isocyanate condensation, composition containing same, method for use, and resulting compositions SCO2, CA2, CA1 ESR1 3840/4885ESR2 3725/4885NPC1 3040/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.