Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11500627 | 0.92 | HCAR2 (0.50) | HCAR2ATMALDH1A1HPGDTSHR | |
| SCHEMBL293240 | 0.87 | GAA (0.50) | HCAR2MGAMGAASIMGAM2 | |
| SCHEMBL11571102 | 0.80 | ATM (0.61) | HCAR2ATMALDH1A1HPGDTSHR | |
| SCHEMBL11066780 | 0.79 | GAA (0.52) | HCAR2MGAMGAASIMGAM2 | |
| SCHEMBL8538532 | 0.78 | NAAA (0.57) | HCAR2ATMALDH1A1HPGDTSHR | |
| SCHEMBL9165492 | 0.77 | NAAA (0.60) | HCAR2ATMALDH1A1HPGDTSHR | |
| SCHEMBL129368 | 0.76 | — | — | |
| SCHEMBL11574796 | 0.76 | NAAA (0.58) | HCAR2ATMALDH1A1HPGDTSHR | |
| SCHEMBL5835931 | 0.75 | MGAM (0.46) | HCAR2MGAMGAASIMGAM2 | |
| SCHEMBL126105 | 0.74 | HCAR2 (0.54) | HCAR2ATMALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664784-B2 | ENANTIOMERIC RESOLUTION | ALBEMARLE CORP (US) | 1999-09-29 | — | — | EP | disclosed |
| US-5457205-A | Substituted thiazoles useful for treatment of diabetes | DR. KARL THOMAE GMBH (DE) | 1995-10-10 | — | — | US | disclosed |