Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.45 |
| ▸ | FAAH | O00519 | 4/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417480 | 0.81 | CYP19A1 (0.40) | MEN1KMT2AMAPTHTTNPSR1 | |
| SCHEMBL8111487 | 0.78 | CNR2 (0.55) | CNR2FAAHCNR1MEN1KMT2A | |
| SCHEMBL8111101 | 0.73 | CNR2 (0.48) | CNR2FAAHCNR1EPHX2MEN1 | |
| SCHEMBL13766918 | 0.73 | CNR2 (0.63) | CNR2FAAHCNR1EPHX2MAPT | |
| SCHEMBL8122218 | 0.73 | ALDH1A1 (0.46) | CNR2FAAHCNR1EPHX2 | |
| SCHEMBL3067076 | 0.67 | CNR2 (0.58) | CNR2FAAHCNR1MAPTHTT | |
| SCHEMBL14263139 | 0.67 | CNR2 (0.50) | CNR2CNR1 | |
| SCHEMBL13766740 | 0.67 | CNR2 (0.54) | CNR2FAAHCNR1EPHX2MAPT | |
| SCHEMBL3076047 | 0.65 | MAPK1 (0.51) | CNR2FAAHCNR1EPHX2MAPT | |
| SCHEMBL8107161 | 0.65 | HSD11B1 (0.49) | CNR2CNR1CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948777-A | ANTIINFLAMMATORY AGENT | SMITHKLINE BEECHAM CORPORATION (US) | 1999-09-07 | — | — | US | disclosed |