Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420486 | 0.83 | FDFT1 (0.43) | PTPN1L3MBTL1MAPK1FDFT1ALDH1A1 | |
| SCHEMBL8418559 | 0.81 | ATM (0.44) | MAPK1FDFT1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL8420062 | 0.75 | FDFT1 (0.47) | FDFT1 | |
| SCHEMBL8968757 | 0.75 | FDFT1 (0.62) | FDFT1 | |
| SCHEMBL8919905 | 0.75 | FDFT1 (0.41) | MAPK1FDFT1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL8919982 | 0.72 | MMP13 (0.46) | MAPK1FDFT1ALDH1A1SMN1; SMN2ESR1 | |
| SCHEMBL8419678 | 0.72 | FDFT1 (0.39) | L3MBTL1MAPK1FDFT1ALDH1A1LMNA | |
| SCHEMBL8918772 | 0.71 | ALDH1A1 (0.39) | FDFT1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8921229 | 0.71 | ATM (0.43) | MAPK1ALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL8422011 | 0.69 | L3MBTL1 (0.50) | PTPN1L3MBTL1MAPK1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919793-A | QUINUCLIDINE DERIVATIVES, SQUALENE SYNTHETASE INHIBITORS, ANTICHOLESTEROL AGENTS | ZENECA LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |