Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8422536 | 0.91 | HTT (0.46) | L3MBTL1LMNAPOLBCASP6CYSLTR2 | |
| SCHEMBL8422462 | 0.90 | L3MBTL1 (0.45) | L3MBTL1LMNAPOLBCASP6CYSLTR2 | |
| SCHEMBL8420268 | 0.87 | MEN1 (0.46) | L3MBTL1LMNAPOLBCA12CA1 | |
| SCHEMBL8422576 | 0.86 | AKR1C2 (0.48) | L3MBTL1LMNACA12CA1CA2 | |
| SCHEMBL8418609 | 0.85 | CA12 (0.43) | L3MBTL1LMNACA12CA1CA2 | |
| SCHEMBL8767956 | 0.85 | L3MBTL1 (0.43) | L3MBTL1LMNAPOLBCASP6CA12 | |
| SCHEMBL8422412 | 0.83 | MEN1 (0.48) | L3MBTL1LMNAPOLBCA12CA1 | |
| SCHEMBL8418915 | 0.81 | HTT (0.41) | L3MBTL1LMNACYSLTR2CA12CA1 | |
| SCHEMBL8419005 | 0.81 | CYSLTR2 (0.45) | L3MBTL1LMNACYSLTR2CA12CA1 | |
| SCHEMBL8420287 | 0.80 | HTT (0.53) | LMNACA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872280-A | RESPIRATORY SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | claimed |
| US-5872280-A | RESPIRATORY SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |
| EP-0791576-A2 | Leukotriene antagonistic benzoic acid derivatives | BAYER AG (DE) | 1997-08-27 | — | — | EP | disclosed |