Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 2/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.48 |
| ▸ | PLK1 | P53350 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA4 | P22748 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8418609 | 0.87 | CA12 (0.43) | CA12CA1CA2CA4CA9 | |
| SCHEMBL8420641 | 0.86 | L3MBTL1 (0.47) | CA12CA1CA2CA4CA9 | |
| SCHEMBL8422536 | 0.85 | HTT (0.46) | CA12CA1CA2CA4CA9 | |
| SCHEMBL8418915 | 0.85 | HTT (0.41) | CA12CA1CA2CA4CA9 | |
| SCHEMBL8422462 | 0.84 | L3MBTL1 (0.45) | CA12CA1CA2CA4CA9 | |
| SCHEMBL8420287 | 0.84 | HTT (0.53) | CA12CA1CA2CA4CA9 | |
| SCHEMBL8419005 | 0.83 | CYSLTR2 (0.45) | CA12CA1CA2CA4CA9 | |
| SCHEMBL8767956 | 0.83 | L3MBTL1 (0.43) | CA12CA1CA2CA4CA9 | |
| SCHEMBL8420660 | 0.81 | PLK1 (0.52) | AKR1C2AKR1C1PLK1SMN1; SMN2LMNA | |
| SCHEMBL8420680 | 0.80 | NR1H4 (0.39) | CA12CA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872280-A | RESPIRATORY SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |
| EP-0791576-A2 | Leukotriene antagonistic benzoic acid derivatives | BAYER AG (DE) | 1997-08-27 | — | — | EP | disclosed |