Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 9/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8422576 | 0.84 | AKR1C2 (0.48) | HTTSMN1; SMN2NR1H4ALDH1A1CA12 | |
| SCHEMBL8418609 | 0.81 | CA12 (0.43) | HTTSMN1; SMN2NR1H4ALDH1A1CA12 | |
| SCHEMBL8420641 | 0.80 | L3MBTL1 (0.47) | HTTSMN1; SMN2NR1H4ALDH1A1CA12 | |
| SCHEMBL8422407 | 0.80 | ALDH1A1 (0.63) | HTTSMN1; SMN2NR1H4ALDH1A1MEN1 | |
| SCHEMBL8422536 | 0.79 | HTT (0.46) | HTTSMN1; SMN2CA12CA1CA2 | |
| SCHEMBL8422462 | 0.79 | L3MBTL1 (0.45) | HTTSMN1; SMN2CA12CA1CA2 | |
| SCHEMBL8419005 | 0.77 | CYSLTR2 (0.45) | HTTSMN1; SMN2ALDH1A1CA12CA1 | |
| SCHEMBL8767956 | 0.77 | L3MBTL1 (0.43) | HTTSMN1; SMN2NR1H4CA12CA1 | |
| SCHEMBL8418915 | 0.77 | HTT (0.41) | HTTSMN1; SMN2NR1H4ALDH1A1CA12 | |
| SCHEMBL8420680 | 0.75 | NR1H4 (0.39) | HTTSMN1; SMN2NR1H4ALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872280-A | RESPIRATORY SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |
| EP-0791576-A2 | Leukotriene antagonistic benzoic acid derivatives | BAYER AG (DE) | 1997-08-27 | — | — | EP | disclosed |